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MSCs are multipotent cells characterized by self-renewal, multilineage differentiation, and immunomodulatory capabilities

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Superoxide dismutases can irreversibly scavenge O 2 .- , and are the core antioxidant enzymes 38,39,40,41

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In the folate/vitamin B12dependent mechanism, folate in the form of 5methyl tetrahydrofolate, derived from 5,10methylene tetrahydrofolate reductase catalyzed tetrahydrofolate modification, donates a methyl group to Hcy catalyzed by the vitamin B12dependent enzyme methionine synthase to form methionine

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