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By up-regulating this cellular protein, TB4 enhances actins positive effects, promoting cell migration and proliferation

doi: 10.1002/14651858.CD003053.pub5 235 XueJLiXLiuPLiKShaLYangXet al

Hexokinase 2 (HK2), which catalyzes the first step of glycolysis, is stabilized by the deubiquitinase CSN5 in HCC, promoting metastasis

While it is uncommon for nausea and vomiting to cause death during pregnancy, there have been reports of morbidities such as Wernicke's encephalopathy, splenic avulsion, oesophageal rupture, pneumothorax, and acute tubular necrosis