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Kombucha also activates SIRT-1 and AMPK, suppressing chronic inflammation via NF-B inhibition, boosting mitochondrial biogenesis and ATP catabolism, while reducing lipogenesis and hepatic cholesterol synthesismechanisms associated with improved energy expenditure and anti-obesity effects

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While the targeted manipulation of gene regulation holds immense promise for enhancing functional phytochemicals in tomatoes, the approach is not without its significant current limitations