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Following 6 wk of ethanol administration, GCLM knockout mice were resistant to alcohol-induced steatosis and exhibited beneficial metabolic and stress responses to chronic ethanol consumption

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However, these perspectives describe the complex interaction between lipid metabolism and autophagy, reveal a novel connection between lipid metabolism and lipophagy, aid the identification of selective receptors for lipophagy, and increase the understanding of the interactions between lipid metabolism and autophagy