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He F, Ji H, Feng L, Wang Z, Sun Q, Zhong C, Yang D, Gai S, Yang P, Lin J

Although non-selective targeting of isozymes could result in undesired side effects, the existence of PDE5-Is with dual impacts on factors contributing to the same pathological condition, particularly multi-factorial diseases, could potentially offer an advantage over the traditional single target-one disease approach

Int Immunopharmacol 34:250258 Chen Q, Chen L, Wu X, Zhang F, Jin H, Lu C, Shao J et al (2016b) Dihydroartemisinin prevents liver fibrosis in bile duct ligated rats by inducing hepatic stellate cell apoptosis through modulating the PI3K/Akt pathway

Ge H, Du J, Zheng J, Xu N, Yao Q, Long S, Fan J, Peng X