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Two of the aforementioned serine residues are located on the more C-terminal loop at the entrance of the substrate channel leading to the respective active site, and phosphorylation of only one of them is sufficient to inactivate pyruvate dehydrogenase, thus demonstrating the out-of-phase coupling between its active sites

Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity

The illness is typified by the emergence of hallucinations, delusions, impaired cognitive processes, and a constellation of adverse symptoms, including diminished emotional expression and communication difficulties [54]

A correlation between vitamin C intake and a reduced incidence of pancreatic cancer has also been described (122)