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Statistical significance was determined using two-sided Fishers exact test for contingency analysis (maturation rate, spindle morphology and euploid rates), One-way ANOVA with a two-sided HolmSidaks multiple comparison test for continuous normally distributed datasets (oocyte diameter), or KruskalWallis with a two-sided Dunns multiple comparison test for continuous non-normally distributed datasets

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One of the many studies available on this topic, a study conducted at the Medical University of South Carolina, found that e-cigarette users smoked 37% fewer cigarettes than non-vapers