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Reasons for CAB+LEN: NNRTI mutations, integrase mutations, high viral loads, continued viremia on CAB/RPV alone 24% were cis/trans female, 42% Black/Af Am, 36% Latinx 94% achieved viral suppression at 8 weeks (47% suppressed at baseline) 71% were on q8wk CAB dosing, though the authors state initially using q4wk dosing may be prudent pending further study for patients with adherence challenges

The mechanism of oxidative cell death Excessive ROS can directly damage organelles, including the plasma membrane, ultimately leading to cell death [71]

Differential Diagnosis The differential for new-onset hyperglycemia or a suspected diabetes diagnosis is broad

Medication Containers (I)