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For instance, a phase II trial assessed the weight loss properties of tesofensine in obese patients and found significant reductions in body weight and visceral fat

It has a wide spectrum of metabolic effects, including induction of apoptosis via ROS production and cytochrome c release (17), inhibition of NADH oxidation (18), and loss of GSH (19)

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With new-generation therapies such as retatrutide and CagriSema producing spectacular outcomes in clinical trials, and oral counterparts such as orforglipron providing even more convenience, people will have access to even more personalized and effective treatments