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Lysine-specific modifications of p53: a matter of life and death

doi: 10.3389/fpls.2013.00198 108 OsorioS.VallarinoJ

Li X, Li J, Zhao Q, Qiao L, Wang L, Yu C (2023) Physiological, biochemical, and genomic elucidation of the Ensifer adhaerens M8 strain with simultaneous arsenic oxidation and chromium reduction

IDO inhibits the function of immune cells through a specific L-Trp depletion pathway, where L-Trp depletion by IDO leads to its dissociation with L-Trp tRNA, thus activating general control non-derepressible 2 (GCN2) due to the presence of its allosteric regulatory site which senses free tRNAs (47, 48)