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Potential Long-Term Risks Although AOD-9604 does not increase IGF-1 levels, there are concerns about its long-term metabolic effects, including: Unknown impact on fat metabolism regulation Since AOD-9604 alters fat-burning pathways, researchers are still investigating whether prolonged use could affect natural fat metabolism

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(Roberti et al., 2023) reported a novel dual-substrate NNMT inhibitor, CC-410 , which stably binds to and exhibits high specificity in inhibiting NNMT

It is available only through research chemical suppliers and some compounding pharmacies, where it is often labeled not for human use to comply with regulations Australia: Classified as a Schedule 4 prescription-only medicine, meaning it can only be legally obtained with a doctors prescription