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V., Prinsen H., and Juchem C., Multiple Sclerosis Diagnosis and Phenotype Identification by Multivariate Classification of in Vivo Frontal Cortex Metabolite Profiles, Scientific Reports 12, no

(2019) Crystal structure of the ergothioneine sulfoxide synthase from Candidatus Chloracidobacterium thermophilum and structure-guided engineering to modulate its substrate selectivity

These approaches provide a variety of therapeutic modalities for controlling blood sugar levels, improving insulin activity, and safeguarding pancreatic cells in the treatment of diabetes

For broader clinical use, however, these benefits require systematic and well-designed clinical validation (64)