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Monoclonal antibodies blocking PD-1, other checkpoint receptors, or their ligands release this brake, enhance tumor-specific T-cell activity, and can induce durable responses in some patients with advanced cancers, including melanoma [11,12,13]

Thus, this study illustrates the complexity of variables (e.g., concentration, dose, form, heat and water treatment, phenotype of maca, part of plant used, pH conditions, route of administration) implicated in the eventual efficacy of a maca product