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J Am Coll Cardiol 43:17311737 Anderson KM, Ferranti EP, Alagha EC, Mykityshyn E, French CE et al (2022) The heart and gut relationship: a systematic review of the evaluation of the microbiome and trimethylamine-N-oxide (TMAO) in heart failure

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Additionally, chondrocyte death is difficult to repair, and a degree of mitochondrial autophagy is necessary for chondrocyte protection when stress occurs (243)

Bone healing acceleration is documented in rat femur fracture studies, indicating that the peptide's regenerative influence extends to mineralized tissue as well as soft connective tissue