After having them for a couple of days and then not, I can tell you with 100% certainty that not only did they take away my pain (which I thought might be in my head, but was definitely not), they made movement less physically taxing, work less mentally draining, and allowed me more freedom. Kim (Suffers with Arthritis & Fibromyalgia): OMG Margaret, that patch is amazing

Caution for vulnerable populations A 2016 literature review on artificial sweeteners in the Indian Journal of Pharmacology reported, there is inconclusive evidence to support most of their uses and some recent studies even hint that these earlier established benefits might not be true. Susceptible populations such as pregnant and lactating women, children, diabetics, migraine, and epilepsy patients should use these products with utmost caution. Review studies on non-sugar sweeteners Two review studies published in 2023 raised health concerns about the class of non-sugar sweeteners, which include acesulfame K, aspartame, advantame, cyclamates, neotame, saccharin, sucralose and stevia
investigated the contribution of NO to the growth of skin lesions in an animal model for AD
Mild side effects may include slight redness or tenderness at the injection site, but these usually resolve quickly.