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GHK-Cu has an excellent safety profile backed by over 50 years of research and more than 70 published studies

A 12-week facial study on 67 women indicated that GHK-Cu cream applied twice daily improved aged skin appearance, increased thickness, reduced wrinkles and strongly stimulated dermal keratinocyte proliferation as determined by histological analysis of biopsies

GHK-Cu supports the anagen (growth) phase of the hair cycle, appears to protect dermal papilla cells from DHT-induced shrinkage, and has been shown in lab studies to increase follicle size and density

(2025) used 0.5 to 1.0 mm needle depth, monthly sessions, and a topical mixture of copper peptides with minoxidil 5% and dutasteride 0.25%