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177,178,179 Aspartic acid (Asp) is an essential energy source for the intestinal mucosa, and studies have shown that Asp can increase the abundance of Akkermansia in the intestine by regulating RIPK1 signaling, maintaining the integrity of the intestinal barrier, and promoting colonic mucosal functional repair

Their bioavailability, or the amount absorbed, varies between oral and IV/IM routes

In order to reduce the risk of infection, the procedure must be done utilizing sterile technique