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SOX2 and SOX2 + cells are essential for production of secretory acini Our lineage tracing analysis confirmed that SOX2 + cells give rise to acinar but not duct cells

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The most frequently reported adverse events were gastrointestinal events, including nausea, vomiting, diarrhea, constipation, or abdominal pain, which affected 79.6% of participants in the cagrilintide-semaglutide group and 39.9% of those in the placebo group

Drug Des Devel Ther 12:20172024 Yang Y, Wang G, Zhang S, Wang H, Zhou W, Ren F, Liang H, Wu D, Ji X, Hashimoto M, Wei J (2022) Efficacy and evaluation of therapeutic exercises on adults with Parkinsons disease: a systematic review and network meta-analysis