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Quercetin inhibits TNF- induced HUVECs apoptosis and inflammation via downregulating NF-kB and AP-1 signaling pathway in vitro

We then examined its proteolytic activity against other potential substrates, including human C3, C3b, C4, C5, factor H (FH), C4 binding protein (C4bp), and IgA, and found that rC0362, but not C412A, cleaved C3 (Fig