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Effects of Light Therapy on Mood and Insulin Sensitivity in Patients With Type 2 Diabetes and Depression: Results From a Randomized Placebo-Controlled Trial

The resulting strategy families correspond to major design objectives: improving pharmacokinetics and biodistribution [33, 37, 53, 66, 67], modulating vascular access and perfusion [11, 12, 15, 68, 69], normalizing or reprogramming stromal barriers [13, 17, 30, 32, 34, 70], enabling endogenous TME-responsive release or activation [46,47,48], reshaping antitumor immunity [29, 35, 71], and integrating imaging with therapeutic intervention [72,73,74]

Avoiding food, conversation, or smiling

Since DM can result in increased hepatic glucose production, as well as lipid metabolism changes, it could result in an inflammatory environment, leading to the development of fatty liver (El-Marasy et al