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As of mid-2026, neither cagrilintide nor retatrutide is FDA- or EMA-approved for any indication, and no legitimate prescription product exists for either

doi: 10.1016/j.biopha.2018.05.007 17 KocaturkNMAkkocYKigCBayraktarOGozuacikDKutluOet al

Mazdutide has demonstrated remarkably low discontinuation rates (near 1% in early trials) compared to retatrutide (12-18% in Phase 3)

After considering these alternative options, we proposed that the lookback period for the median allowed amount, 10th and 90th percentile allowed amounts, and count of allowed amounts (discussed in a later section) be based on EDI 835 ERA transaction data from no longer than 12 months prior to posting the MRF