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Key ways it appears to mimic or amplify natural gastrointestinal and tissue repair mechanisms observed in animal studies: Strongly upregulates angiogenesis through multiple pathways (VEGF, EGR-1, FAK-paxillin) in injured tissues, similar to the bodys own response during normal wound healing and tendon/ligament repair

Compared with placebo-treated controls, NAC patients showed significant improvements in neurocognition (processing speed) and a reduction of positive symptoms among patients with high peripheral oxidative status

141,142 Recent development of microneedle and polymeric wafers with minimal invasiveness provides sustained drug release for CNS disease management which circumvent the BBB

Researchers may also use animal models that overexpress abnormal tau proteins or inject tau aggregates to study their role in the disease