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Among the strategies developed, there are agents capable of neutralizing LPS, such as cationic lipids or cationic proteins, which are effective in binding LPS in compounds that are difficult to separate, useful to evading LPS-mediated immune stimulation

However, when the structural and functional integrity of neural cells is compromised and the permeability of the bloodbrain barrier increases, it disrupts blood biomarkers, allowing GFAP to be released from tissues into the bloodstream

The mechanisms underlying these beneficial effects include the modulation of oxidative stress, inflammation, and apoptosis pathways [8]