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Comparing the therapeutic efficacy of NAC or combination of NAC and cimetidine in patients with acute AALI, no significant improvement was found in hepatoprotective activities between intravenous administration of cimetidine (300 mg per 6 h) and the sole NAC treatment (Ebrahimi et al., 2015)

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Important considerations include: Avoiding use with serotonin-increasing medications such as SSRIs as there is risk of serotonin syndrome when combined with those drugs Avoiding use in individuals with G6PD deficiency Consulting a physician before considering its use He also highlights the importance of quality

Forms of DSIP supplementation DSIP is typically available in the form of a lyophilized (freeze-dried) powder, which must be reconstituted with sterile water or bacteriostatic water before administration (you may or may not need a chemistry degree to use this)