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Kang et al., 2009)

Through TULP1 knockout models in zebrafish, scientists found that TULP1 deficiency causes early-onset retinal degeneration through up-regulating ferroptosis-related genes, increasing the shrinkage of mitochondria, iron and lipid droplet deposition and reducing mitochondria cristae, and increasing the death of photoreceptors via ferroptosis (Jia et al., 2022)

In lung adenocarcinoma, CAF-specific long non-coding RNA, LINC01614, packaged in exosomes derived from CAFs, interacts directly with ANXA2 and p65 to promote NF-B activation