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Nature 433:769773 Lindpaintner K (2002) The impact of pharmacogenetics and pharmacogenomics on drug discovery

5 L of the sample was loaded

The strength of this insulin-driven hypersecretion of IGF-1 was shown in the past by the observation that hypoinsulinemia induced by prolonged fasting can completely normalize serum IGF-1 levels in acromegaly patients [36,37]