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These findings are supported by mechanistic investigations that have identified multiple pathways through which environmental toxicants can induce DNA fragmentation in spermatozoa, including oxidative stress, mitochondrial dysfunction, and direct genotoxic effects (67)

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Tohidi et al., 2017), researchers are increasingly adopting modular strategies to present complex epitopes like the membrane-proximal external region (MPER) or the fusion peptide (Mogus et al., 2020

Indeed, in astrocytes, Linuron synergized with IL-1 and TNF to induce unfolded protein accumulation and boosted pro-inflammatory gene expression such as Nos2, IL6, CSF2, and CLl2 ( Brain tissue samples from MS patients have been analyzed, and elevated levels of inflammatory responses, like in mouse astrocytes exposed to Linuron, were found (Wheeler et al., 2019)