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Smaller droplets referred as fraction D2 were then isolated after an ultracentrifugation at 100 000 g for 1 h at d = 1

Funding This research was supported by the INSERM, Universit Cte dAzur, the Fondation ARC pour la Recherche contre le Cancer (Equipe Labellise 20222025), the Canceropole PACA, a grant from PLBio (R19003AP-20192023), ITMO cancer 20192023 and the Association Laurette Fugain (ALF)