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Zimmermann MB

Although plasma levels are typically in the micromolar range, epithelial surfaces (e.g., lungs) maintain high extracellular GSH concentrations to protect against inhaled oxidants, such as hypochlorous acid (HOCl) (11-14)

Among other issues are differences in capacity and affinity for the oxidizing substrate, a potential role of thiol peroxidases in H 2 O 2 perception and, as mentioned above, the importance of other peroxidases in H 2 O 2 -dependent substrate oxidations or ROS generation

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