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The eye area becomes affected early and prominently during this aging process, creating hollow sunken eyes, hollow upper eyelids with loose upper eyelid skin, and hollow under eye area with under eye bags or dark circles or tear trough deformity. Fat loss from around the eye area (temples, brows, cheeks) further exacerbates the problem, contributing to the fall of the eyebrows and cheeks

Physical or emotional trauma: Events such as car accidents or significant psychological stress can trigger the onset of fibromyalgia

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It has been shown to fully interact with dopamine system, centrally and peripherally