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Description

The LD 50 values were 400 mg/kg in mice, 385 mg/kg in rats, and 140 mg/kg in rabbits and dogs though these values were dependent on infusion rate

Sci Rep (2021) 11(1):10472

In therapeutics, EVs are available to participate in the drug delivery process, and the drug as a cargo to be transported through EVs requires proper encapsulation into EVs, and this entails analyzing the composition of EVs by metabolomics for better drug delivery [194]