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While HGF may serve as the link between obesity and cancer, it should be noted that given the association of HGF levels with tumor progression, metastasis and less favorable response to cancer treatment, employing HGF for the modulation of IR or treating diabetes may be significantly limited by its cancer-promoting properties

Standard target: 99% purity

Dena Dubals lab at UCSF (Cell Reports, 2017) showed that peripheral klotho fragment administration enhanced cognition and neural resilience in young, aging, and -synuclein transgenic mice through NMDA receptor-dependent mechanisms

Administration Routes Subcutaneous (most accessible): Lower abdomen, standard subQ injection technique