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Notably, despite caspase-1s essential role in IL-1 maturation, its involvement in GSDMD cleavage was excluded by comparable GSDMD-N elevation in Casp1 KO and WT cochleae after noise exposure (Fig

Integrating lncRNA-based biomarker panels into GBM diagnosis and personalized treatment strategies could enhance patient stratification, therapeutic decision-making, and overall clinical outcomes