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Additionally, based on the immunohistochemistry images, the researchers state that CJC-1295 caused an increase in total pituitary RNA and GH mRNA, suggesting that proliferation of somatotroph cells had occurred. CJC-1295 Peptide and Infertility Research dating back to the early 1990s suggests that CJC-1295 and other growth hormone-releasing factor (GRF) analogs may promote ovulation in infertile female organsims, as these models reportedly showed a significant increase of both follicular fluid IGF-I levels (compared to the previous cycle) and plasma GH levels immediately . (9) Ovulation is considered to be dependent on insulin-like growth factor-1 (IGF-1) and likely influenced by growth hormone (GH) release and cycling

Ciebiera M, Wlodarczyk M, Zgliczynska M, et al

10.1111/j.1471-4159.2011.07545.x J