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Cannabidiol, a Major Phytocannabinoid, As a Potent Atypical Inhibitor for CYP2D6. Drug Metabolism and Disposition, vol

The air we breathe

EUROPE, MIDDLE EAST & AFRICA GLUTATHIONE MARKET SIZE, BY SPECIALTY STORES, 2018-2032 (USD MILLION) TABLE 304

Using structure-based analyses and cell models, including patient fibroblasts, of this variant, we found that the missense variant destabilized a critical loop, which disrupted the active site and caused a substantial loss of enzymatic function