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Additionally, it plays a role in immune function, metabolism, sperm cell formation, tissue repair, and enzyme support

It also seeks to inform therapeutic strategies and improve diagnosis and prognostic assessment

pointed out that the p53-p21 axis could delay the onset of ferroptosis induced by cysteine deprivation in human Ht-1080 fibrosarcoma cells, which facilitated the adaptation of cancer cells to metabolic stress [34]

They found combining the differential expression of both ATPB and ACON produced a diagnostic biomarker with a sensitivity of 85%, specificity of 72% and area under the receiver-operator characteristic (ROC) curve (AUC) of 0.793