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(A ) D2 hermaphrodite gonad stained for lipid (oil red O) and imaged with DIC optics

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or an N-oxide, crystalline form, hydrate, or pharmaceutically acceptable salt thereof, with the proviso that: when R 3 is ethyl, R 1 and R 2 cannot be both H, O, or when R 3 is ethyl and at least one of R 1 or R 2 is H, R 1 or R 2 cannot be Suitable and preferred compounds that are used in the pharmaceutical compositions of the present invention are disclosed above in formulas (I)-(III), including the particular SRS compounds also identified above

Artemisinin and deoxyartemisinin isolated from Artemisia annua L