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Tell the health care provider of any existing medical conditions or concerns (need to identify risk factors) Tell the health care provider of any existing lifestyle concerns, such as alcohol use, other drug use, sleeping habits, diet, and stress levels (need to identify lifestyle factors that can influence ASD-related medication use and ASD management) Tell the nurse or health care provider if you experience any pain that increasingly becomes more severe or interferes with your quality of life Keep track of your health, medication use, and health concerns via an app, diary, or journal (self-monitoring for any changes) Tell the health care provider right away if you are having thoughts of hurting yourself or others (possible increased risk of suicidality) Take all prescribed medications as indicated and ask questions about medications and possible other treatment options, such as non-pharmacological options or surgeries Tell the health care provider if you notice any changes while taking medications or on other treatments to manage autism-associated behaviors and mood changes (potential worsening or improving health situation) Research Findings The National Institutes of Health and other evidence-based journals provide extensive, publicly available literature on medications

doi: 10.1038/s41522-020-00146-8, 27 ChengW.XuF.GaoL.LiuJ

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Thus, studies propose combining dietary serine and glycine starvation with PHDGH inhibitors, which show synergistic inhibition of one-carbon metabolism and cancer growth in both in vitro and in vivo experiments (Tajan et al., 2021)