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Use preferably within 30 days of reconstitution

Additionally, chrysin exhibited anti-tumor activity against choriocarcinoma cells through modification of mitochondrial membrane potential, disruption of Ca 2+ levels in cytosol, enhancing generation of reactive oxygen species (ROS), and inducing lipid peroxidation, which affects intracellular Ca 2+ homeostasis resulting in cancer cell damage [86]

indicates that PAC, in the absence of adequate, physiological levels of GSH, may give rise to genotoxic quinone imine metabolites ( The production of quinone imine metabolite is the primary responsible for PAC liver and kidney toxicity

K.Ballester RoigM