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Biomaterials 238 , 119844 (2020)

For more specific answers to this question, be sure to discuss this at length with Dr

In addition to these direct cytotoxic effects of MPO activity, elevated MPO activity increases reactive oxygen species (ROS) formation, MMP activation, and the production of inducible NO synthase, and inflammatory cytokines (i.e., IL-1 and tumor necrosis factor-) (Ekdahl et al., 2003