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Therefore, zinc has a protective potential against metabolic syndrome-associated oxidative stress through induction of transcription factors (including (ARE)-Nrf2 signaling) and a subsequent up-regulation of enzymatic and non-enzymatic antioxidants, induction of metallothionein synthesis, its structural role in Cu,Zn-SOD (SOD1), and, finally, its direct antioxidant activity

Competing interests Anteneh Tesfaye Tefera, Debebe Worku Dadi, and Mulualem Tamiru Kassa are employees of BioTEI Inc., supplier of the Moringa seed meal

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2019;33(1_supplement):662.21