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Heme oxygenase-1 induction may explain the antioxidant profile of aspirin

Chollet A, Mourey L, Lherbet C, Delbot A, Julien S, Baltas M, et al

Given that low lactate dehydrogenase levels represent a high mitochondrial metabolic state, this finding is consistent with the observation that cells with high levels of lipoylated TCA enzymes and a hyperactive mitochondrial respiratory rate are more sensitive to elesclomol