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Top Facts about COPD and Smoking Airway Epithelial Cells Smoke Exposure in COPD The pathogenesis of COPD. Cigarette smoke activates macrophages (1), Download Scientific Diagram Smoking doesn't just affect your lungs it destroys them over time. COPD (Chronic Obstructive Pulmonary Disease) is one of the most common and preventable causes of breathlessness and lung failure. The
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