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Elevated RRM2 levels also correlate with MYCN expression levels and poorer survival outcomes in NB patients (47)

For the cyanocobalamin component, while generally considered safe with few absolute contraindications, certain conditions warrant caution

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Synthse chimique [modifier | modifier le code] Synthse totale [modifier | modifier le code] La synthse chimique de la vitamine B 12 (en)Robert Burns Woodward [61] et Albert Eschenmoser en 1972 [62] , [63] , et reste une russite majeure de la synthse organique totale