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Many studies reported the beneficial effect of Curcumin on diabetic peripheral neuropathy through antioxidant activity ( In the present study, curcumin could suppress diabetes-induced microglial activation, consistent with the results of Furthermore, the present study found that curcumin could rescue the spinal cord neurons from diabetes-induced injury as demonstrated through the restoration of the number of NeuN positive cells, consistent with the results of The anti-apoptotic effect of curcumin, as reported here, may be due to its role in the restoration of the Nrf2/HO-1 and NF-kB pathways

Gabbay E, Zigmond E, Pappo O, Hemed N, Rowe M, Zabrecky G, Cohen R, Ilan Y

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