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Figure 4 Astrocytes, key regulators of neuroinflammation and brain iron homeostasis, also contribute to PD pathogenesis

The methyl malonyl-CoA epimerase transforms D-methyl malonyl-CoA into L-stereoisomer (L-methyl malonyl-CoA)

In agreement with this, we observed the highest expression of PrP in cholangiocarcinoma nodes in the liver of Atp7b / mice, whereas PrP depletion almost completely prevented tumor growth