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Nevertheless, most addictive substances, like smoking cigarettes, alcohol, and drugs, cause the brain to shut down its own dopamine-producing mechanism, which in turn causes individuals to continue eating these substances

With around 14% of the adult population still smoking (2019), this could prove very costly

Of the states for which the authors had data, the highest rates of outbound smuggling (least amount of net inbound smuggling) occur in Wyoming (49.2 percent outbound smuggling), Delaware (34.4 percent), New Hampshire (31.4 percent), and Virginia (30.4 percent)