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doi: 10.1038/s41467-020-18871-1 116 MarchesiJ

The liver is capable of numerous reactions which generally serve to make the substance to be eliminated more polar and water soluble to subsequently be excreted in bile or urine (Phase I reactions: oxidoreductases and hydrolases) and to make the substance less toxic (Phase II reactions: transferases)

Detailed mechanism of squalene epoxidase inhibition by terbinafine

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