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Fava C, Kantarjian HM, Jabbour E, O'Brien S, Jain N, Rios MB, Garcia-Manero G, Ravandi F, Verstovsek S, Borthakur G , Shan J, Cortes J

Description IGF-1 LR3 1mg IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a synthetic analog of human Insulin-like Growth Factor-1 modified with two structural changes from native IGF-1: an arginine substitution at position 3 and an N-terminal extension of 13 amino acids

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In addition to the interaction with RAGE, several members of the TLR family, including TLR2, 4, 5, and 9, are also able to interact with HMGB1 [6366]