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Indeed, in baboons, injected alpha-synuclein has been found to be transported from the gut to the brain and vice versa via the bloodstream ( The bloodstream is affected early on in both Alzheimers (Pierzchliska et al., 2021), so much so in fact that it has been argued that Alzheimers may be just as much a vascular disease as a neurological one (Fulop et al., 2018)

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Although both PKC and PKA have been reported to be the upstream kinase for Ser184 of GSTP in MGR3 human glioblastoma cells (51), our study indicated that only cPKC interacted with GSTP and mediated LPS-stimulated GSTP phosphorylation

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